The CIMP Phenotype in BRAF Mutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort
Figure 5
BRAF mutation and CIMP status in p16 and IGFBP7 methylated polyps. A comparative analysis was performed to assess the percentage of BRAF mutant (a) and CIMP-H (b) samples with p16 and IGFBP7 methylation. The SSAs showed the highest number of p16 and combined p16/IGFBP7 methylated samples in the BRAF mutant and CIMP-H groups and this was closely followed by the HPs.