Research Article
ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
Table 3
Genotypic frequency in European Americans.
| | Genotypes | NOR ()
(freq.%) | MAL ()
(freq.%) | OR (95% CI) | value |
| | ABCB1 G2677T/A | | | 0.34 (0.12~0.97) | 0.043 | | GG | 16 (27.6) | 23 (36.5) | TT versus (GT+GG) | | | GT | 28 (48.3) | 32 (50.8) | | | | TT | 14 (24.1) | 6 (9.5) | | | | TA | 0 (0) | 1 (1.6) | | | | GA | 0 (0) | 1 (1.6) | | | | ABCB1 C3435T | | | 0.39 (0.16~0.92) | 0.033 | | CC | 13 (22.4) | 16 (25.4) | TT versus (CT+CC) | | | CT | 26 (44.8) | 37 (58.7) | | | | TT | 19 (32.8) | 10 (15.9) | | | | ABCC1 G-260A | | | 1.96 (0.56–6.91) | 0.293 | | GG | 4 (6.9) | 8 (12.7) | GG versus (GA+AA) | | | GA | 29 (50.0) | 27 (42.9) | | | | AA | 25 (43.1) | 28 (44.4) | | | | ABCG2 C421T | | | 2.81 (0.11–70.31) | 0.530 | | CC | 45 (77.6) | 52 (82.5) | TT versus (CT+CC) | | | CT | 13 (22.4) | 10 (15.9) | | | | TT | 0 (0) | 1 (1.6) | | |
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