Difference in Early Activation of NF-κB and MCP-1 in Acinar-Cell-Rich versus Fibrotic Human Pancreas Exposed to Surgical Trauma and Hypoxia
Figure 2
NF-κB expression in acinar-cell-rich ((a), (b)) and fibrotic ((c), (d)) pancreata. (a) and (c) are 15-minute sample and (b) and (d) represent 4-hour time points. Arrowheads indicate representative NF-κB-expressing nuclei in acinar cells. NF-κB-positive fibroblasts were rare (open arrow in (a)), the fibroblast nuclei being predominantly negative (arrows). The increase in NF-κB activation is more prominent in acinar-cell-rich pancreata ((a) and (b)) than in fibrotic pancreata ((c) and (d)). Control stainings were negative (e).
