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First author, Year | Psychophysiological parameters | Experimental paradigm | Inclusion criteria | AP group | controls | Age AP group (range) in years |
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Apley, 1956 [27] | CNS: EEG (not specified) | EEG recording of resting and evoked responses (hyperpnoea and photic stimulation) | Apley and Naish’s criteria | 133 | 133 healthy | NN (3–14*) |
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Rubin, 1967 [14] | ANS: Pupillary diameter | Reactivity on cold pressor task | More than 6 months, at least weekly frequency | 13 | 12 healthy | 10.6 (8–14) |
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Apley, 1971 [15] | ANS: Pupillary diameter | Reactivity on cold pressor task | Not specified (recurrent AP) | 16 | 14 healty 20 emotional disturbance | 9.8 (5–13) |
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Battistella, 1992 [16] | ANS: Pupillary diameter | Reactivity on phenylephrine eye-drops | Apley and Naish’s criteria + dysautonomic symptoms | 18 | 15 healthy | 12.8 (10–16) |
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Feuerstein, 1982 [17] | ANS: HR, digital blood volume pulse EMG | Reactivity on cold pressor task | Apley and Naish’s criteria | 10 | 9 organic ill 10 healthy | NN (9–14) |
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Alfvén, 1994 [30] | ES: blood plasma oxytocin, cortisol, and prolactin | Blood plasma concentrations of hormones after an overnight fast period | Apley and Naish’s criteria | 40 | 34 organic ill | 10 (7–16) |
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Olafsdottir, 2001 [22] | ANS: HRV (RSA via deep breathing test), EDA | Baseline comparison | Apley and Naish’s criteria | 25 | 23 healthy | 10.7 (7–15) |
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Dorn, 2003 [19] | ANS: HR, SBP ES: salivary cortisol | Reactivity on mental and social stress (Trier Social Stress Test) | Apley and Naish’s criteria | 14 | 14 healthy 14 anxiety | 12.7 (NN) |
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Alfvén, 2004 [31] | ES: blood plasma cortisol | Blood plasma concentrations of hormones after an overnight fast period | Apley and Naish’s criteria | 23 | 21 healthy | 9.5 (NN) |
ES: blood plasma oxytocin | Blood plasma concentrations of hormones after an overnight fast period | Apley and Naish’s criteria | 32 | 15 IBD 79 healthy | 9.6 (6–15*) |
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Törnhage, 2006 [33] | ES: salivary cortisol | Diurnal variation of salivary cortisol | Apley and Naish’s criteria | 31 | 306 healthy | 10.8 (6–18) |
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Hermann, 2008 [28] | CNS: EEG N1, P2, and P3 | Attentional bias to painful and innocuous somatic stimuli | Apley and Naish’s criteria | 14 | 15 healthy | 12.1 (10–15) |
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Puzanovova, 2009 [25] | ANS: HRV (frequency-based) | Reactivity on success/failure in a cognitive task | Apley and Naish’s criteria | 45 | 22 healthy | 11.6 (9–16*) |
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Bakker, 2010 [20] | CNS: EMG ANS: EDA | Auditory startle paradigm | Rome III FAP or IBS | 20 | 23 healthy 25 anxiety | 12.4 (NN) |
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Friesen, 2010 [26] | ANS: HRV (time- and frequency-based) | Reactivity following a test meal or rapid water loading, respectively | Rome III FD | 9 resp. 8 | 28 healthy | 13 (11–17) |
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Sowder, 2010 [23] | ANS: HRV (time- and frequency-based) | Baseline comparison | Not exactly specified (most probable Apley and Naish’s criteria) | 20 | 10 healthy | 12.6 (5–17) |
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Dufton, 2011 [18] | ANS: HR | Reactivity on mental and social stress, cold pressure task | Apley and Naish’s criteria | 21 | 21 healthy 21 anxiety | 11.1 (8–16*) |
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Jarrett, 2012 [24] | ANS: HRV (frequency-based) | 24 h monitoring | Rome III FAP or IBS | 100 | 62 healthy | 8.9 (7–10) |
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Seino, 2012 [29] | CNS: EEG latencies of I wave, III wave, IV wave, and V wave | Brainstem auditory evoked potentials following click sounds | Presence of at least one of seven GI symptoms in the last two weeks | 75 | 66 without GI symptoms | 7 (all at the same age) |
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