Proanthocyanidin from Grape Seed Extracts Protects Indomethacin-Induced Small Intestinal Mucosal Injury
Figure 2
Microscopic findings in the rat small intestine. (a) and (b) Erosions induced by indomethacin showed focal villous necrosis and reduced epithelial height. (c) and (d) Ulcers induced by indomethacin showed deep excavation of mucosa and exposed submucosal layer. Marked inflammatory cell infiltration was noted in the submucosal space. (e) and (f) Transmural inflammatory infiltration was present beyond the ulcer formation (hematoxylin-eosin stain, ×40).
