Serum Activins and Follistatin during the Treatment of Chronic Hepatitis C Genotypes 1 and 4 and Their Correlations with Viral Load and Liver Enzymes: A Preliminary Report

Table 2

Demographic and laboratory characteristics of the patients according to study groups.

	NC; (𝑛=40)	PC; (𝑛=33)	4 W; (𝑛=19)	12 W; (𝑛=22)	24 W; (𝑛=19)	𝑅 (𝑛=21)	NR; (𝑛=11)
Age (years)	39±7.4	49.8±16.3	41.5±13.4	42±11.5	44.9±12.5	46±13.4	42.1±18.1
Gender
Male	20 (50%)	16 (48.4%)	11 (57.9%)	15 (68.1%)	13 (68.4%)	12 (57.1%)	5 (45.5%)
Female	20 (50%)	17 (51.6%)	8 (42.1%)	7 (31.9%)	6 (31.6%)	9 (42.9%)	6 (55.5%)
Genotype
G1	ND	14 (42.4%)	10 (52.9%)	10 (47.3%)	10 (55.5%)	11 (52.3%)	3 (27.3%)
G4	ND	19 (57.6%)	9 (41.1%)	12 (52.7%)	9 (45.5%)	10 (47.7%)	8 (72.7%)
Viral load; at diagnosis (IU/mL)	ND	1256194±555544	1397057±481355	1089313±617246	999187±400348	1048288±303944	1165716±457946
Albumin (g/dL)	4.4±0.2	3.66±0.46^a	3.88±0.43^a	3.84±0.53^a	4.03±0.23^a	3.91±0.39^a	3.95±0.48^a
ALP (IU/L)	79.4±21.6	120.2±51.8	112.4±35.8	100.6±39.3	85.8±26.5	87.8±32.6	110.09±42.8
ALT (IU/L)	28±11.2	63±25.7^a	53.3±24.7^a	56.3±26.2^a	45±14.3^b	37.6±20.8^b	38.9±18.7^b
AST (IU/L)	21±7.6	43.4±17.2^a	39.3±16.2	38.3±12.6	31.2±8.3^b,c	28±10.7^b,c	42.4±20.4^a,e,f
APRI	0.37±0.07	0.85±0.29^a	0.55±0.23^a	0.77±0.28^a	0.66±0.2^a,b	0.65±0.21^a,b	0.72±0.3^a

ND = not done, ^a𝑃<0.05 compared to NC, ^b𝑃<0.05 compared to PC, ^c𝑃<0.05 compared to 4 W, ^d𝑃<0.05 compared to 12 W, ^e𝑃<0.05 compared to 24 W, and ^f𝑃<0.05 compared to 𝑅.