Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature

Table 1

Characteristics of the included studies.

Author	Year	Location	Single versus multicenter	𝑛, total	𝑛, IBD (CD/UC)	𝑛, control	Control composition	Mean age, IBD (CD/UC)	Mean age, control
Machiels et al. [8]	2013	Belgium	Single	214	0/127	87	Healthy controls	43	41.5
Varela et al. [12]	2013	Spain	Single	176	0/116	31	Healthy controls	40	32
Swidsinski et al. [13]	2008	Germany	Single	422	82/105	32	Healthy controls	35/41	40
Dörffel et al. [9]	2012	Germany	Single	171	50/0	25	Healthy controls	39	48
Vermeiren et al. [14]	2012	Belgium	Single	12	0/6	6	Healthy controls	Not reported	Not reported
Joossens et al. [15]	2011	Belgium	Single	207	68/0	55	Healthy controls	Not reported	Not reported
Wang et al. [16]	2013	China	Single	76	21/34	21	Healthy controls	Not reported	Not reported
Jia et al. [17]	2010	UK	Single	73	20/14	18	Healthy controls	Not reported	Not reported
Sokol et al. [18]	2009	France	Single	133	22/13	27	Healthy controls	37/40	36
Andoh et al. [19]	2012	Japan	Multicenter	188	67/0	121	Healthy controls	30	32
Willing et al. [20]	2009	Sweden	Single	20	6/0	6	Healthy controls	Not reported	Not reported

IBD: inflammatory bowel disease; CD: Crohn’s disease; UC: ulcerative colitis.