Research Article

Molecular Features and Methylation Status in Early Onset (≤40 Years) Colorectal Cancer: A Population Based, Case-Control Study

Table 1

Clinicopathological features of 33 colorectal adenocarcinomas (and patients) developed ≤40 years (1984–2008) compared to patients with cancer onset >60 years.

Technical detailsPatients with onset ≤40 years, (%)Patients with onset >60 years, (%)

Age of onset of diseaseMin
Max
Mean
11
40
35
61
85
73

SexFemale
Male
8 (24)
25 (76)
11 (27)
30 (73)

Tumor location in the large bowelRight colon
Left colon
Rectum
7 (21)
17 (52)
9 (27)
12 (29)
19 (47)
10 (24)

Stage (Dukes)A
B
C
D
5 (15)
7 (21)
12 (37)
9 (27)
7 (17)
9 (22)
14 (34)
11 (27)

Tumor differentiation Low-grade
High-grade
Mucinous
19 (58)
8 (24)
6 (18)
31 (76)
8 (19)
2 (5)