Circulating Oxidized Low-Density Lipoproteins and Antibodies against Oxidized Low-Density Lipoproteins as Potential Biomarkers of Colorectal Cancer
Table 1
Demographic, clinical, and biochemical parameters in healthy control and total CRC patients and in colon and rectum subgroups. Data are presented as median (interquartile range Q25–Q75).
(A) Control ()
(B) Total CRC ()
(C) Colon ()
(D) Rectum ()
value 1 (A versus B)
value 2 (A versus C versus D)
Gender (M/F)
23/12
44/29
28/24
16/5
0.130
0.097
Age (years)
57 (55–62)a
70 (58–76)
70 (63–76)a
69 (67–76)a
<0.001*
<0.001*
BMI (kg/m2)
25.4 (23.7–26.9)
24.5 (23.1–26.1)
24.7 (23.6–26.2)
23.6 (21.9–25.8)
0.194
0.072
CEA (µg/L)
2.2 (0.4–3.2)
1.6 (0.7–4.2)
1.6 (0.7–4.8)
1.7 (0.7–3.8)
0.214
0.490
oxLDL (U/L)
62.0 (48.0–67.3)
60.1 (48.4–84.1)
64.4 (51.2–88.1)
49.3 (46.6–69.1)
0.287
0.172
o-LAB (U/L)
282.0 (219.6–409.2)b
488.0 (286.0–1046.0)
578.6 (285.6–1131.1)b,c
352.8 (285.6–450.8)c
0.003*
0.002*
TC (mg/dL)
164.5 (138.3–185.0)
175.0 (148.0–194.0)
183.5 (156.0–196.5)d
148.0 (125.0–176.0)d
0.519
0.003*
HDL-C (mg/dL)
60.2 (55.7–65.0)e
56.0 (48.0–65.0)
58.5 (51.5–67.0)f
51.0 (40.0–59.0)e,f
0.316
0.004*
LDL-C (mg/dL)
103.0 (86.0–127.0)
119.0 (93.0–128.0)
117.0 (93.0–128.0)
120.0 (92.0–129.0)
0.206
0.450
TG (mg/dL)
154.0 (134.0–159.0)
134.0 (117.0–152.0)
137.0 (122.0–152.5)
123.0 (106.0–152.0)
0.151
0.331
Glu (mg/dL)
97.0 (95.0–101.0)
96.5 (86.0–110.0)
96.0 (86.0–108.0)
97.0 (94.0–120.0)
0.364
0.661
M/F: male/female; *statistically significant; a for A versus C and A versus D; b for A versus C; c for C versus D; d for C versus D; e for A versus D; f for C versus. D.
