Review Article

Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?

Table 3

An overview of the biomarker potential of lncRNAs for esophageal cancer.

lncRNACancer typeSampleExpressionClinical applicationReference

HOTAIRESCCTissueUpUnfavorable prognosis[148]

LOC285194ESCCTissueDownFavorable prognosis and prediction of response to chemotherapy[158]

POU3F3ESCCPlasmaUpDiagnosis[143]

UCA1ESCCTissueUpUnfavorable prognosis[151]

SPRY4-IT1 ESCCTissueUpUnfavorable prognosis[152]

PCAT-1ESCCTissueUpUnfavorable prognosis[153]