Assessing the Effect of Leptin on Liver Damage in Case of Hepatic Injury Associated with Paracetamol Poisoning

Table 1

The numeric density of the necrotic cells in the specimens obtained from the liver samples.

Group	Numeric density of the necrotic hepatocytes (cm^2)
Control	4 ± 1.41^a.b
LEP 20 µg/kg	5.5 ± 1.87^b.c
PARA 2 g/kg	63 ± 16.26^a.c
PARA 2 g/kg + LEP 10 µg/kg	7.3 ± 1.21^b.c
PARA 2 g/kg + LEP 20 µg/kg	6.83 ± 2.48^b.c

Group 1: the control group; Group 2: 20 µg/kg leptin; Group 3: 2 g/kg paracetamol; Group 4: 2 g/kg paracetamol + 10 µg/kg leptin; Group 5: 2 g/kg paracetamol + 20 µg/kg leptin. LEP: the group receiving leptin, PARA: the group receiving paracetamol. comparison of the control group and paracetamol group, comparison of the control group and treatment group, and comparison of the paracetamol group and the treatment group. was considered significant.