Clinical Study
Clinical Impact of Prophylactic Antibiotic Treatment for Self-Expandable Metallic Stent Insertion in Patients with Malignant Colorectal Obstruction
Table 1
Comparison of clinical characteristics in PA versus non-PA groups.
| | Characteristics | PA group () | Non-PA group () | value |
| | Age, years (mean ± SD) | 67.6 ± 11.7 | 65.0 ± 12.6 | 0.128 | | Sex (male/female) | 94 (64.8%)/51 (35.2%) | 54 (68.4%)/25 (31.6%) | 0.659 | | Body mass index (kg/m2) | 21.6 ± 2.7 | 21.8 ± 2.7 | 0.538 | | Aims (preoperative/palliative) | 82 (56.6%)/63 (43.4%) | 44 (55.7%)/35 (44.3%) | 1.000 | | Diabetes mellitus | 21 (14.5%) | 11 (13.9%) | 1.000 | | WBC (×1000), (/mm3) | 8.1 ± 3.2 | 7.5 ± 2.7 | 0.198 | | ANC (×1000), (/mm3) | 5.8 ± 3.0 | 5.2 ± 2.5 | 0.124 | | CRP (mg/dL) | 4.6 ± 6.6 | 2.4 ± 3.4 | 0.001 | | Potassium (mEq/L) | 3.9 ± 0.5 | 3.9 ± 0.8 | 0.556 | | Abdominal pain | 112 (77.2%) | 54 (68.4%) | 0.154 | | Abdominal tenderness | 66 (45.5%) | 22 (27.8%) | 0.010 | | Degree of obstruction (total/subtotal) | 42 (29.0%)/103 (71.0%) | 19 (24.1%)/60 (75.9%) | 0.530 | | Mechanical ileus | 80 (55.2%) | 24 (27.8%) | <0.001 | | Carcinomatosis peritonei | 18 (12.4%) | 7 (8.9%) | 0.509 | | Obstruction site | | | 0.857 | | Ascending colon | 3 (2.1%) | 2 (2.5%) | | | Hepatic flexure | 8 (5.5%) | 5 (6.3%) | | | Transverse colon | 3 (2.1%) | 0 (0.0%) | | | Splenic flexure | 7 (4.8%) | 5 (6.3%) | | | Descending colon | 8 (5.5%) | 5 (6.3%) | | | Rectosigmoid colon | 116 (80.0%) | 62 (78.5%) | |
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PA, prophylactic antibiotics; , number; WBC, white blood cell; ANC, absolute neutrophil count; CRP, C-reactive protein; significantly different.
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