Research Article
Amrubicin Monotherapy for Patients with Platinum-Refractory Gastroenteropancreatic Neuroendocrine Carcinoma
| | | Grade | | | 1 | 2 | 3 | 4 | 3 + 4 (%) |
| | Hematologic | | | | | | | Leukopenia | 3 | 3 | 2 | 0 | 2 (20) | | Neutropenia | 4 | 0 | 2 | 2 | 4 (40) | | Anemia | 3 | 2 | 5 | 0 | 5 (50) | | Thrombocytopenia | 4 | 0 | 0 | 0 | 0 | | Total bilirubin elevation | 3 | 0 | 0 | 0 | 0 | | ALT elevation | 7 | 0 | 0 | 0 | 0 | | AST elevation | 5 | 0 | 0 | 0 | 0 | | Hyponatremia | 7 | 2 | 0 | 0 | 0 | | Hyperkalemia | 3 | 0 | 0 | 0 | 0 | | Nonhematologic | | | | | | | Anorexia | 6 | 3 | 1 | 0 | 1 (10) | | Nausea | 5 | 3 | 1 | 0 | 1 (10) | | Vomiting | 1 | 0 | 0 | 0 | 0 | | Fatigue | 4 | 3 | 1 | 0 | 1 (10) | | Mucositis | 3 | 0 | 0 | 0 | 0 | | Diarrhea | 0 | 0 | 0 | 0 | 0 | | Constipation | 4 | 4 | 0 | 0 | 0 |
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