Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity

Figure 1

The figure represents the major organs involved in the modulation of peripheral signals (ghrelin, nesfatin-1, gastrin, leptin, adiponectin, GLP-1, CCK, and gut microbiota) after Roux-en-Y gastric bypass (RYGB) surgery. The increase/decrease in the signals is designed by arrows. CB1: cannabinoid receptor type 1; CCK: cholecystokinin; GLP-1: glucagon-like peptide 1.