Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2015, Article ID 630273, 7 pages
http://dx.doi.org/10.1155/2015/630273
Research Article

Diagnostic Value of Semiquantitative Analysis of Dynamic Susceptibility Contrast Magnetic Resonance Imaging with GD-EOB-DTPA in Focal Liver Lesions Characterization: A Feasibility Study

1School of Medicine, University of Milano-Bicocca, 20900 Milan, Italy
2Department of Diagnostic Radiology, H. S. Gerardo Monza, Milan, Italy

Received 16 November 2014; Accepted 20 April 2015

Academic Editor: Haruhiko Sugimura

Copyright © 2015 Davide Ippolito et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. V. Pandharipande, G. A. Krinsky, H. Rusinek, and V. S. Lee, “Perfusion imaging of the liver: current challenges and future goals,” Radiology, vol. 234, no. 3, pp. 661–673, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. D. M. Parkin, F. Bray, J. Ferlay, and P. Pisani, “Estimating the world cancer burden: GLOBOCAN 2000,” International Journal of Cancer, vol. 94, no. 2, pp. 153–156, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. F. Donati, P. Boraschi, R. Gigoni, S. Salemi, F. Falaschi, and C. Bartolozzi, “Focal nodular hyperplasia of the liver: diffusion and perfusion MRI characteristics,” Magnetic Resonance Imaging, vol. 31, no. 1, pp. 10–16, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. E. K. Brodsky, E. M. Bultman, K. M. Johnson et al., “High-spatial and high-temporal resolution dynamic contrast-enhanced perfusion imaging of the liver with time-resolved three-dimensional radial MRI,” Magnetic Resonance in Medicine, vol. 71, no. 3, pp. 934–941, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. Itai and O. Matsui, “Blood flow and liver imaging,” Radiology, vol. 202, no. 2, pp. 306–314, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. S. B. Fox, G. Gasparini, and A. L. Harris, “Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs,” Lancet Oncology, vol. 2, no. 5, pp. 278–289, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Brasch and K. Turetschek, “MRI characterization of tumors and grading angiogenesis using macromolecular contrast media: status report,” European Journal of Radiology, vol. 34, no. 3, pp. 148–155, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Chandarana and B. Taouli, “Diffusion and perfusion imaging of the liver,” European Journal of Radiology, vol. 76, no. 3, pp. 348–358, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. R. K. G. Do, H. Rusinek, and B. Taouli, “Dynamic contrast-enhanced MR imaging of the liver: current status and future directions,” Magnetic Resonance Imaging Clinics of North America, vol. 17, no. 2, pp. 339–349, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. A. R. Kambadakone and D. V. Sahani, “Body perfusion CT: technique, clinical applications and advances,” Radiologic Clinics of North America, vol. 47, no. 1, pp. 161–178, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Monto and T. L. Wright, “The epidemiology and prevention of hepatocellular carcinoma,” Seminars in Oncology, vol. 28, no. 5, pp. 441–449, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. H. B. El-Serag and K. L. Rudolph, “Hepatocellular carcinoma: epidemiology and molecular carcinogenesis,” Gastroenterology, vol. 132, no. 7, pp. 2557–2576, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. D. J. Atkinson, D. Burstein, and R. R. Edelman, “First-pass cardiac perfusion: evaluation with ultrafast MR imaging,” Radiology, vol. 174, no. 3, pp. 757–762, 1990. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Berthezène, V. Vexler, O. Clément, A. Mühler, M. E. Moseley, and R. C. Brasch, “Contrast-enhanced MR imaging of the lung: assessments of ventilation and perfusion,” Radiology, vol. 183, no. 3, pp. 667–672, 1992. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Warach, J. M. Levin, D. L. Schomer, B. L. Holman, and R. R. Edelman, “Hyperperfusion of ictal seizure focus demonstrated by MR perfusion imaging,” The American Journal of Neuroradiology, vol. 15, no. 5, pp. 965–968, 1994. View at Google Scholar · View at Scopus
  16. P. Reimer, S. Saini, K. K. Kwong, M. S. Cohen, R. Weissleder, and T. J. Brady, “Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement,” Journal of Magnetic Resonance Imaging, vol. 4, no. 3, pp. 331–335, 1994. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Materne, A. M. Smith, F. Peeters et al., “Assessment of hepatic perfusion parameters with dynamic MRI,” Magnetic Resonance in Medicine, vol. 47, no. 1, pp. 135–142, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. B. E. van Beers, R. Materne, L. Annet et al., “Capillarization of the sinusoids in liver fibrosis: Noninvasive assessment with contrast-enhanced MRI in the rabbit,” Magnetic Resonance in Medicine, vol. 49, no. 4, pp. 692–699, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Annet, R. Materne, E. Danse, J. Jamart, Y. Horsmans, and B. E. Van Beers, “Hepatic flow parameters measured with MR imaging and Doppler US: correlations with degree of cirrhosis and portal hypertension,” Radiology, vol. 229, no. 2, pp. 409–414, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. T. R. Bader, A. M. Herneth, W. Blaicher et al., “Hepatic perfusion after liver transplantation: noninvasive measurement with dynamic single-section CT,” Radiology, vol. 209, no. 1, pp. 129–134, 1998. View at Publisher · View at Google Scholar · View at Scopus
  21. D. A. C. Leggett, B. B. Kelley, I. H. Bunce, and K. A. Miles, “Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocols,” Radiology, vol. 205, no. 3, pp. 716–720, 1997. View at Publisher · View at Google Scholar · View at Scopus
  22. B. E. van Beers, I. Leconte, R. Materne, A. M. Smith, J. Jamart, and Y. Horsmans, “Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severity,” The American Journal of Roentgenology, vol. 176, no. 3, pp. 667–673, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. S. S. Abdullah, J. B. Pialat, M. Wiart et al., “Characterization of hepatocellular carcinoma and colorectal liver metastasis by means of perfusion MRI,” Journal of Magnetic Resonance Imaging, vol. 28, no. 2, pp. 390–395, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Materne, B. E. van Beers, A. M. Smith et al., “Non-invasive quantification of liver perfusion with dynamic computed tomography and a dual-input one-compartmental model,” Clinical Science, vol. 99, no. 6, pp. 517–525, 2000. View at Publisher · View at Google Scholar · View at Scopus