Review Article

Positron Emission Tomography for the Response Evaluation following Treatment with Chemotherapy in Patients Affected by Colorectal Liver Metastases: A Selected Review

Table 1

EORTC response criteria for 18F-FDG PET/CT.

CMRComplete resolution of [18F]-FDG uptake within the tumour volume so that it was indistinguishable from surrounding normal tissue

PMRReduction of a minimum of 15 ± 25% in tumour 18F-FDG SUV after one cycle of chemotherapy and greater than 25% after more than one treatment cycle

SMDIncrease in tumour 18F-FDG SUV of less than 25% or a decrease of less than 15% and no visible increase in extent of 18F-FDG tumour uptake (20% in the longest dimension)

PMDIncrease in 18F-FDG tumour SUV of greater than 25% within the tumour region defined on the baseline scan and visible increase in the extent of 18F-FDG tumour uptake (20% in the longest dimension) or the appearance of new 18F-FDG uptake in metastatic lesions