Research Article

Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy

Table 3

Potential risk factors contributing to postoperative complications after pancreaticoduodenectomy.

With complications ()Without complications () value

Mean age (years)60 ± 156 ± 10.023
Gender (male)67 (58.3%)127 (57.7%)1.000
Preoperative biliary drainage20 (17.4%)27 (12.3%)0.246
Smoking pack-years (>20)38 (33%)70 (32.1%)0.902
Preoperative hypertension20 (17.4%)38 (17.3%)1.000
Preoperative cardiac disease10 (8.8%)8 (3.6%)0.071
Preoperative diabetes mellitus14 (12.3%)17 (7.7%)0.232
White blood cells (×109/L)7.1 ± 0.36.5 ± 0.20.072
Hemoglobin (g/L)121.6 ± 1.9118.9 ± 1.10.201
Platelet count (×109/L)209.2 ± 8.5214.7 ± 5.40.565
Alanine aminotransferase (U/L)102.9 ± 5.580.0 ± 7.10.013
Aspartate aminotransferase (U/L)87.2 ± 4.367.2 ± 5.20.003
Albumin (g/L)37.4 ± 0.541.9 ± 3.40.330
Total bilirubin (μmol/L)167.8 ± 10.6168.9 ± 15.70.953
Prothrombin time (s)12.7 ± 0.112.8 ± 0.10.348
Fibrinogen (g/L)4.1 ± 0.14.3 ± 0.10.171
Carcinoembryonic antigen (ng/mL)8.8 ± 5.33.7 ± 0.20.345
Carbohydrate antigen 125 (U/mL)22.9 ± 2.332.7 ± 7.50.386
Carbohydrate antigen 19-9 (U/mL)486.8 ± 206.1860.2 ± 271.30.360
Pathological diagnosis0.477
 Benign disease4 (3.5%)14 (6.4%)
 Malignant disease111 (96.5%)206 (93.7%)
Tumor diameter (cm)4.3 ± 0.64.1 ± 0.50.774
Jejuna feeding tube placement30 (26.1%)43 (19.5%)0.209
Combined vessel resection3 (2.6%)7 (3.2%)1.000
Blood loss (mL)427.0 ± 34.7497.3 ± 41.20.260