The Increased Expression of CCL20 and CCR6 in Rectal Mucosa Correlated to Severe Inflammation in Pediatric Ulcerative Colitis
Table 1
Patients characteristics.
CUC ()
AUC ()
value
Gender (male/female)
17/7
70/47
n.s.
Age at UC diagnosis, years (median, range)
13.0 (1–15)
29.0 (16–82)
Duration of disease before surgery, years (median, range)
3 (0.3–28)
5 (0.1–28)
n.s.
Clinical severity at operation,
Mild
10 (41.7%)
51 (43.6%)
n.s.
Moderate
10 (41.7%)
50 (42.7%)
Severe
4 (17.6%)
16 (14.3%)
Extent of disease at operation,
Pancolitis
21 (87.5%)
95 (81.2%)
n.s.
Left-sided colitis
3 (12.5%)
22 (18.8%)
Pathological Inflammation in rectum,
Mild (grades 0, 1)
6 (14.0%)
10 (10.2%)
n.s.
Moderate (grades 2, 3)
11 (25.6%)
34 (34.7%)
Severe (grades 4, 5)
26 (60.4%)
44 (45.1%)
CUC; childhood-onset; AUC; adult-onset. Correlations were evaluated using Fisher’s exact probability test or chi-squared test, the Mann-Whitney test, and Kruskal-Wallis test. A value of less than 0.05 was considered to be statistically significant.
