Nuclear Factor Kappa B, Matrix Metalloproteinase-1, p53, and Ki-67 Expressions in the Primary Tumors and the Lymph Node Metastases of Colorectal Cancer Cases

Table 2

NF-κB, MMP-1, p53, and Ki-67 expressions in the primary tumor and the metastatic lymph nodes.

	Colon ()		Rectum ()		All tumors ()
	Primary tumor	Metastatic lymph node	Primary tumor	Metastatic lymph node	Primary tumor	Metastatic lymph node
NF-κB
Negative	11 (17.2%)	6 (9.4%)	7 (15.2%)	4 (8.7%)	18 (16.4%)	10 (9.1%)
Weak	6 (9.4%)	5 (7.8%)	6 (13%)	6 (13%)	12 (10.9%)	11 (10%)
Moderate	20 (31.2%)	22 (34.4%)	14 (30.5%)	13 (28.3%)	34 (30.9%)	35 (31.8%)
Strong	27 (42.2%)	31 (48.4%)	19 (41.3%)	23 (50%)	46 (41.8%)	54 (49.1%)
MMP-1
Negative	12 (18.8%)	21 (32.8%)	8 (17.4%)	15 (32.6%)	20 (18.2%)	36 (32.7%)
Weak	29 (45.3%)	16 (25%)	21 (45.7%)	11 (23.9%)	50 (45.5%)	27 (24.6%)
Moderate	14 (21.8%)	25 (39.1%)	11 (23.9%)	19 (41.3%)	25 (22.7%)	44 (40%)
Strong	9 (14.1%)	2 (3.1%)	6 (13%)	1 (2.2%)	15 (13.6%)	3 (2.7%)
p53
Negative	5 (7.8%)	2 (3.1%)	4 (8.7%)	1 (2.2%)	9 (8.2%)	3 (2.7%)
Weak	11 (17.2%)	6 (9.4%)	13 (28.3%)	4 (8.7%)	24 (21.8%)	10 (9.1%)
Moderate	31 (48.4%)	36 (56.3%)	19 (41.3%)	23 (50%)	50 (45.5%)	59 (53.6%)
Strong	17 (26.6%)	20 (31.2%)	10 (21.7%)	18 (39.1%)	27 (24.5%)	38 (34.6%)
Ki-67
Negative	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)
Weak	32 (50%)	13 (20.3%)	20 (43.5%)	8 (17.4%)	52 (47.3%)	21 (19.1%)
Moderate	21 (32.8%)	31 (48.4%)	15 (32.6%)	18 (39.1%)	36 (32.7%)	49 (44.5%)
Strong	11 (17.2%)	20 (31.3%)	11 (23.9%)	20 (43.5%)	22 (20%)	40 (36.4%)