Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors

Table 1

Clinical and laboratory findings in 64 patients with hypomagnesemia (<0.75 mmol/L) while being on long-term management with a proton-pump inhibitor. Numerical data are presented as median and interquartile range (which extends from the value at centile 25 to that at centile 75 and includes half of the data points) and categorical data as relative frequency.

Age, years	66 [59–73]
Gender, ♂/♀	30/34
Circulating magnesium level, mmol/L	0.24 [0.15–0.30]
Duration of treatment with proton-pump inhibitor, years	4 [3–10]
Urinary magnesium excretion, low/normal	42/0
Circulating calcium level, low/normal	58/2
Parathyroid hormone level, low-normal/high	42/2
Circulating potassium level, low/normal	27/4

Assessed exclusively in subjects with total calcium level <2.20 mmol/L. <3.5 mmol/L.