Research Article

Liver Cirrhosis/Severe Fibrosis Is a Risk Factor for Anastomotic Leakage after Colorectal Surgery

Table 2

Results of the univariate analyses of the risk factors of anastomotic leakage after colonic anastomosis.

Risk factorAnastomotic leak ()No anastomotic leak () value

Mean age (SD)68.8 (14.9)64.9 (14.4)0.028
Male gender0.021
Median ASA score (Range)2 (1–4)2 (1–5)0.156
Cardiac comorbidities0.322
Vascular comorbidities1.000
Diabetes0.022
Pulmonary comorbidities0.396
Tobacco abuse0.437
Obesity1.000
Dementia0.142
Immunosuppressive drugs0.010
Nonsteroidal anti-inflammatory drugs1.000
Presence of cancer1.000
Presence of peritonitis1.000
Large bowel obstruction1.000
Liver cirrhosis or severe fibrosis0.024
Mean (SD) white blood cell count 8.5 (3.8)8.2 (4.0)0.300
Mean (SD) haemoglobin level12.7 (2.4)13.3 (2.0)0.084
Mean (SD) sodium level138.9 (4.2)140.0 (3.1)0.471
Mean (SD) potassium level4.1 (0.5)4.1 (1.1)0.757
Mean (SD) creatinine level88.4 (48)79.6 (43.6)0.131
Mean (SD) albumin level37.6 (4.8)40.2 (5.7)<0.001

SD: standard deviation; ASA: American Society of Anesthesiologists.