Research Article
Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases
Table 3
Immunohistochemical expression of TIMP-1 and TIMP-2 in glandular tubes and inflammatory cells in tissues of ulcerative colitis and Crohn’s disease.
| Protein expression | Ulcerative colitis (UC) | Crohn’s disease (CD) | Glandular cells (% of cases) | Inflammatory cells (% of cases) | Glandular cells (% of cases) | Inflammatory cells (% of cases) | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 |
| TIMP-1 | 18.8 | 12.5 | 6.3 | 62.5 | 25 | 31.2 | 6.3 | 37.5 | 22.2 | 11.1 | 0 | 66.7 | 22.2 | 55.6 | 22.2 | 0 | TIMP-2 | 10 | 45.5 | 31.8 | 18.2 | 40.9 | 31.8 | 9.1 | 18.2 | 12.5 | 62.5 | 12.5 | 12.5 | 66.7 | 11.1 | 0 | 22.2 |
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0: absent, 1: weak, 2: moderate, and 3: strong.
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