Research Article
Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d’Ivoire
Table 1
Demographic, clinic, and biologic variables.
| | Parameters |
All patients
| Complications or death | | No | Yes | | | |
| | Age (years) [median (range)] | 34 (72) | 33.5 (54) | 35 (69) | 0.17 | | Sex (male) [ (%)] | 146 (90.7) | 88 (93.6) | 58 (86.6) | 0.2 | | Pulse (pulsations/minute) [median (range)] | 98 (72) | 95 (50) | 110 (72) | 0.0001 | | Hemoglobin (g/dL) [median (range)] | 13.8 (9) | 14 (5) | 13.6 (9) | 0.13 | | Hematocrit (%) [median (range)] | 41 (23) | 41 (7) | 41 (23) | 0.64 | | WBC (102/mL) [median (range)] | 110 (320) | 107 (110) | 130 (320) | 0.0001 | | Platelets count (103 cel/mL) [median (range)] | 199 (493) | 206 (492) | 190 (425) | 0.06 | | Prothrombin time (%) [median (range)] | 89.5 (52) | 90 (33) | 88 (52) | 0.18 | | Creatinine (g/dL) [median (range)] | 17.8 (95) | 13 (17) | 19 (95) | 0.02 | | Kalemia (Meq/mL) [median (range)] | 3.7 (1.9) | 3.7 (1.5) | 3.6 (1.8) | 0.01 | | Natremia (Meq/mL) [median (range)] | 136 (33) | 137 (27) | 134 (33) | 0.02 | | Arterial hypertension (yes) [ (%)] | 9 (5.6) | 6 (6.4) | 3 (4.5) | 0.73 | | Smoking (yes) [ (%)] | 126 (78.3) | 78 (83) | 48 (71.6) | 0.12 | | Anti-inflammatory drugs (yes) [ (%)] | 59 (36.6) | 34 (36.2) | 25 (37.3) | 1.00 | | Comorbidities (yes) | 119 (73.9) | 8 (8.5) | 19 (28.4) | 0.003 | | Surgeons skills (yes) [ (%)] | | | | 0.12 | | Junior | 57 (35.4) | 37 (39.4) | 20 (29.9) | | | Senior | 104 (64.6) | 57 (60.6) | 47 (70.1) | | | Intra-abdominal fluid collection [ (%)] | | | | 0.0001 | | Bile-like fluid | 121 (75.2) | 90 (95.7) | 31 (46.3) | | | Purulent | 39 (24.2) | 3 (3.2) | 36 (53.7) | | | Site of perforation [ (%)] | | | | 0.3 | | Antrum | 75 (46.6) | 40 (42.6) | 35 (52.2) | | | Duodenum | 86 (53.4) | 54 (57.4) | 32 (47.8) | | | ASA score [ (%)] | | | | 0.0001 | | ASA1 | 0 (0.0) | 0 (0.0) | 33 (49.3) | | | ASA2 | 127 (78.9) | 94 (100) | 34 (50.7) | | | ASA3 | 34 (21.1) | 0 (0.0) | 0 (0.0) | | | ASA4 | 0 (0.0) | 0 (0.0) | 0 (0.0) | | | ASA5 | 0 (0.0) | 0 (0.0) | 0 (0.0) | | | Hospital admission delay (hours) [ (%)] | | | | 0.0001 | | ≤24 hours | 73 (45.3) | 54 (57.5) | 19 (28.4) | | | 24–48 hours | 50 (31.1) | 26 (27.7) | 24 (35.8) | | | 48–72 hours | 18 (11.2) | 11 (11.7) | 7 (10.5) | | | >72 hours | 20 (12.4) | 3 (3.2) | 17 (25.4) | | | Surgical intervention delay (hours) [ (%)] | | | | 0.0001 | | ≤24 hours | 23 (14.3) | 6 (6.4) | 17 (25.4) | | | >24 hours | 138 (85.7) | 88 (93.6) | 50 (74.6) | | | Duration of surgical intervention (minutes) | 76 (97) | 76 (68) | 75 (97) | 0.6 | | Duration of hospital stay (days) | | | | 0.0001 | | [mean (SD)] | 9.2 (5) | 8 (1.8) | 11 (7.1) | | | [median (range)] | 8 (36) | 8 (12) | 11 (37) | | | Complications [ (%)] | 36 (22.4) | — | 36 (22.4) | | | Death [ (%)] | 31 (19.3) | — | 31 (19.3) | |
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SD: standard deviation.
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