A Comparison of Short- and Long-Term Therapeutic Outcomes of Infliximab- versus Tacrolimus-Based Strategies for Steroid-Refractory Ulcerative Colitis

Table 3

Cox proportional hazard model for relapse in Tac group.

Parameter	Multivariate analysis (Cox proportional hazard model)
	HR	95% CI	value
Sex			0.79
Male	1
Female	1.14	0.41–3.25
Age at start of the treatment (y)			0.058
20	1
20	11.6	0.92–156.1
Disease duration at the treatment (y)			0.68
5	1
5	1.35	0.33–6.54
Disease extension			0.59
Left-sided colitis	1
Extensive colitis	1.34	0.47–4.38
Response to corticosteroids			0.97
Dependence	1
Refractory	0.98	0.17–4.48
Concomitant use of thiopurine			0.027
Yes	1
No	6.83	1.27–32.4
Continuing use of Tac beyond 3 months			0.018
Yes	1
No	8.33 × 10^8	1.56–1.8 × 10^290

HR, hazard ratio; CI, confidence interval.