Prognostic Impact of mRNA Expression Levels of HER1–4 (ERBB1–4) in Patients with Locally Advanced Rectal Cancer

Figure 2

Distribution of mRNA expression values in analyzed biopsies. Normalized mRNA expression values (40-ΔCq) of RT-qPCR evaluated HER (ERBB) family marker genes and MKI67 are presented. Lowest expression levels were observed for ERBB3 and ERBB4 and highest expression for ERBB2 and MKI67 (box and whiskers plots ranging from minimum to maximum). Gene expression values were compared by two-way Mann-Whitney test ().