Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages
Table 2
Clinical characteristics of the included patients after surgery.
Items
BCLC stages A1–A4 ()
BCLC stages B-C ()
MgiBC + SAMe
MgiBC
value
MgiBC + SAMe
MgiBC
value
Postoperative ICU stay (days)
1.2 ± 0.2
1.2 ± 0.4
1.00
1.2 ± 0.1
1.2 ± 0.2
1.00
Patients with postoperative complications ()
36
43
0.84
63
79
<0.01
Biliary fistula
5
6
0.94
21
21◆
0.65
Poor wound healing
12
15▲
0.86
21●
19
0.91
Wound infection
8
6
0.41
7
13■
0.09
Abdominal infection
2
5
0.33
3
3
0.87
Intestinal obstruction
0
1
0.35
3
5
0.36
Pulmonary infection
4
3
0.56
2
5
0.18
Peritoneal effusion
3
5▲
0.60
6●
11◆
0.12
Subphrenic abscess
2
3
0.76
3
7■
0.13
Surgical resection
Limited resection
81
103
0.20
153
133
0.90
Left lateral segmentectomy
14
11
0.31
29
25
0.94
Left hemihepatectomy
11
17
0.41
35
37
0.38
Extended left hemihepatectomy
2
1
0.48
5
2
0.33
Right hemihepatectomy
11
5
0.06
12
9
0.71
Extended right hemihepatectomy
0
0
—
1
0
0.34
Surgical data
Surgical time (min)
196.4 ± 63.1
187.4 ± 59.3
0.24
231.5 ± 112.9
225.7 ± 105.9
0.57
Surgical hemorrhage (mL)
232.4 ± 99.4
219.9 ± 110.1
0.34
348.7 ± 148.8
366.3 ± 153.2
0.22
Postsurgical hospital stay (days)
16.7 ± 5.7
17.5 ± 5.3
0.24
20.6 ± 7.1
21.0 ± 6.9
0.55
▲One patient in group 1 with postoperative poor wound healing also exhibited peritoneal effusion. ●Three patient in group 2 with postoperative poor wound healing also exhibited peritoneal effusion. ◆Two patients in group 2 with biliary fistulae exhibited peritoneal effusion. ■Three patients in group 2 with subphrenic abscess exhibited wound infection.