D-Dimer and Carcinoembryonic Antigen Levels: Useful Indicators for Predicting the Tumor Stage and Postoperative Survival

Table 1

Relationship between the investigated parameters and the plasma D-dimer and serum CEA levels.

		⁢D-dimer		⁢CEA
		Median (ng/mL)		Median (ng/mg)
Tumor localization
Colon	94	1.10	0.472	26.1	0.621
Rectum	40	0.96		26.9
Differentiation
Well	18	1.10	0.04	26.8	0.207
Middle	94	1.15		27.3
Poor/mucinous	22	1.80		33.1
Tumor diameter (mm)
<20 mm	6	1.31	0.276	2.8	0.615
20–50 mm	86	1.25		23.5
>50 mm	42	1.28		36.6
Wall invasion (N0, M0)
T1	5	0.14	0.0001^+	2.9	0.0001^+
T2	16	0.39		3.7
T3	70	0.80		15.6
T4	18	1.30		50.5
Lymph node (any T, M0)
Negative	52	0.55	0.0004	4.8	0.02
Positive	54	0.96		40.8
Metastasis (any T and N)
No	106	0.78	>0.001	3.20	>0.001
Yes	28	2.53		4.80
Stage
1	14	0.30	0.001^+	3.20	0.001^+
2	34	0.66		4.80
3	58	0.98		12.5
4	28	2.53		102.7

Mann–Whitney test; Kruskal-Wallis test; Spearman’s rank correlation test.