Review Article

Local Ablative Strategies for Ductal Pancreatic Cancer (Radiofrequency Ablation, Irreversible Electroporation): A Review

Table 1

Efficacy of IRE on PDAC.

AuthorNumber of patientsApproachType of studySurvival (mo.)

Martin et al. [23]54Open ()
Percutaneously ()
Propensity-matched comparison with standard chemo- or chemoradiation20.2

Martin et al. [24]200OpenData from multicenter registry24.9

Trueba-Arguiñarena et al. [25]1PercutaneouslyCase reportf-up 12 mo.

Narayanan et al. [26]43PercutaneouslyProspective16.2

Belfiore et al. [27]20PercutaneouslyRetrospective12.9

Pai et al. [28]5PercutaneouslyPhase-1 safety and feasibilityRange 1–6 mo.

Paiella et al. [29]10OpenPhase-1 safety and feasibilityMedian 6.4,
range 2.9–15.9