Duodenal Rare Neuroendocrine Tumor: Clinicopathological Characteristics of Patients with Gangliocytic Paraganglioma

Figure 3

(a) Photomicrograph showing a low-power field of the gangliocytic paraganglioma (GP) site with a dense proliferation of epithelioid cells. Nested and compactly arranged epithelioid cells comprise the majority of the tumor (HE staining; magnification, ×100; the scale bar represents 300 μm). (b) Photomicrograph showing a high-power field of the GP site. The epithelioid cells have round to oval-shaped nuclei, inconspicuous nucleoli, and eosinophilic cytoplasm. Spindle-shaped cells surround the nests of epithelioid cells and are aligned in a single layer (HE staining; magnification, ×400; the scale bar represents 100 μm). (c) Photomicrograph showing a low-power field of the GP site with sporadic proliferation of epithelioid cells. A chaotic arrangement of epithelioid cells and a predominance of stromal cells are seen (HE staining; magnification, ×100; the scale bar represents 300 μm). (d) The epithelioid cells show a random arrangement, and spindle cells in the stroma are arranged in an irregular pattern (HE staining; magnification, ×400; the scale bar represents 100 μm).

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