Research Article

Response to Pegylated Interferon Plus Ribavirin in Patients with Hepatitis C Virus Genotype 6a Infection from Guangdong and Guangxi Province of China

Table 1

The baseline characteristics of patients with different HCV genotype infection.

CharacteristicsHCV-6a ()HCV-2/3 ()HCV-1b () value
(24 w, )(48 w, )

Age (years)34.2 ± 11.636.6 ± 10.636.5 ± 14.0636.7 ± 13.030.639
BMI22.0 ± 4.022.1 ± 3.922.1 ± 2.6222.4 ± 3.930.36
Male ()40 (62.5%)59 (63.3%)62 (60.2%)163 (62.9%)0.857
IDU ()17 (26.6%)25 (28.1%)14 (13.6%)24 (9.3%)<0.001
Blood transfusion ()15 (23.4%)21 (23.6%)37 (35.9%)149 (57.5%)<0.001
Family history of HCC ()4 (6.2%)6 (6.7%)4 (3.9%)7 (2.7%)0.302
PEG-IFNα-2a ()50 (78.1%)67 (75.3%)85 (82.5%)223 (86.1%)0.094
ALT (U/L)82.9 ± 8.180.0 ± 6.987.9 ± 3.078.1 ± 9.00.955
HCV RNA (IU/mL)6.1 ± 1.06.2 ± 1.15.6 ± 1.16.4 ± 0.90.106
Cirrhosis ()6 (9.4%)5 (5.6%)9 (8.7%)37 (14.3%)0.118

BMI, body mass index; IDU, intravenous drug use; HCC, hepatocellular carcinoma; ALT, alanine aminotransferase; HCV RNA, hepatitis C virus ribonucleic acid; cirrhosis, the cut point of ≥14.5 kpa for ≥F4 stage fibrosis; value comparing the different genotype groups.