Clinical Study

Infliximab Combined with Enteral Nutrition for Managing Crohn’s Disease Complicated with Intestinal Fistulas

Table 1

The clinical characteristics of 42 patients with CD.

Clinical featuresConventional group ()IFX group ()

Average age (year)32.1 ± 11.831.6 ± 11.7
Sex (male, %)13 (59%)12 (60%)
Average CDAI score309.9 ± 69.3325.6 ± 70.8
Duration of disease
 <12 months2 (9.1%)2 (10.0%)
 12–36 months14 (63.6%)13 (65.0%)
 >36 months6 (27.3%)5 (25.0%)
Lesion site
 Terminal ileum (L1 type)6 (27.3%)6 (30.0%)
 Colon (L2 type)7 (31.8%)6 (30.0%)
 Ileum and colon (L3 type)9 (40.9%)8 (40.0%)
Disease behavior
 No stenosis or penetration (B1 type)0 (0%)0 (0%)
 Stenosis (B2 type)0 (0%)0 (0%)
 Penetration (B3 type)22 (100%)20 (100%)
Stage of disease activity
 Moderate active stage14 (63.6%)13 (65.0%)
 Severe active stage8 (36.4%)7 (35.0%)
Combined drug therapy
 5-Aminosalicylic acid22 (100%)20 (100%)
 Methylprednisolone22 (100%)0 (0%)
 Imuran22 (100%)0 (0%)
Associated with anal lesions16 (72.7%)14 (70.0%)
History of intestinal surgery5 (22.7%)6 (30.0%)
Extraintestinal manifestations4 (18.2%)4 (20.0%)

Compared with the IFX treatment group: .