Clinical Study
Infliximab Combined with Enteral Nutrition for Managing Crohn’s Disease Complicated with Intestinal Fistulas
Table 1
The clinical characteristics of 42 patients with CD.
| Clinical features | Conventional group () | IFX group () |
| Average age (year) | 32.1 ± 11.8 | 31.6 ± 11.7 | Sex (male, %) | 13 (59%) | 12 (60%) | Average CDAI score | 309.9 ± 69.3 | 325.6 ± 70.8 | Duration of disease | | | <12 months | 2 (9.1%) | 2 (10.0%) | 12–36 months | 14 (63.6%) | 13 (65.0%) | >36 months | 6 (27.3%) | 5 (25.0%) | Lesion site | | | Terminal ileum (L1 type) | 6 (27.3%) | 6 (30.0%) | Colon (L2 type) | 7 (31.8%) | 6 (30.0%) | Ileum and colon (L3 type) | 9 (40.9%) | 8 (40.0%) | Disease behavior | | | No stenosis or penetration (B1 type) | 0 (0%) | 0 (0%) | Stenosis (B2 type) | 0 (0%) | 0 (0%) | Penetration (B3 type) | 22 (100%) | 20 (100%) | Stage of disease activity | | | Moderate active stage | 14 (63.6%) | 13 (65.0%) | Severe active stage | 8 (36.4%) | 7 (35.0%) | Combined drug therapy | | | 5-Aminosalicylic acid | 22 (100%) | 20 (100%) | Methylprednisolone | 22 (100%) | 0 (0%) | Imuran | 22 (100%) | 0 (0%) | Associated with anal lesions | 16 (72.7%) | 14 (70.0%) | History of intestinal surgery | 5 (22.7%) | 6 (30.0%) | Extraintestinal manifestations | 4 (18.2%) | 4 (20.0%) |
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Compared with the IFX treatment group: .
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