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Gastroenterology Research and Practice
Volume 2016 (2016), Article ID 6474651, 6 pages
Research Article

The Prevalence of Headache in Crohn’s Disease: Single-Center Experience

1Umraniye Education and Research Hospital, Department of Neurology, Umraniye, 34764 Istanbul, Turkey
2Mehmet Akif İnan Training and Research Hospital, Department of Gastroenterology, 63300 Şanlıurfa, Turkey
3Umraniye Education and Research Hospital, Department of Gastroenterology, Umraniye, 34764 Istanbul, Turkey

Received 13 November 2015; Accepted 30 December 2015

Academic Editor: Tomm Bernklev

Copyright © 2016 Ulker Anadol Kelleci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. This study is aimed at studying the prevalence and characteristics of different types of headaches in patients with Crohn’s disease. Materials and Methods. 51 patients in Crohn’s disease group (F/M: 26/25) and 51 patients in control group (F/M: 27/24) were involved. Patients in Crohn’s disease group were diagnosed and monitored according to European Crohn’s and Colitis Organization diagnostic criteria. The control group composed of healthy subjects with similar age and sex to Crohn’s disease group. Headache was classified using the International Headache Society II criteria. Results. Headache was reported by 35/51 (68.6%) patients in Crohn’s disease group and 21/51 (41.2%) patients in the control group. The prevalence of headache was statistically high in the group with Crohn’s disease (OR: 3.125 (95% CI: 1.38–7.04); ). Comparing two groups with respect to their subtypes of headaches resulted in that the tension-type headache was statistically () higher in Crohn’s disease group (26/51) than in the control group (12/51). However, no significant difference was found in the migraine-type headache (). Conclusions. This study indicates that the prevalence of headache is high in patients with Crohn’s disease and most commonly associated with the tension-type headache.