Clinical Study
Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association
Table 2
Association between obesity and erosive esophagitis.
| | Body mass index | Normal esophagus
() | Erosive esophagitis
() | OR (95% CI) | value | for trend |
| | Normal weight (18.5–24.9 kg/m2) | 569 (35.79) | 121 (18.31) | 1 | | | | Overweight (25–29.9 kg/m2) | 563 (35.41) | 272 (41.15) | 2.66 (2.01–3.52) | <0.01 | <0.01 | | Class I obesity (30–34.9 kg/m2) | 298 (18.74) | 168 (25.42) | 3.62 (2.64–4.95) | <0.01 | | Class II obesity (35–39.9 kg/m2) | 106 (6.67) | 46 (6.96) | 2.84 (1.83–4.38) | <0.01 | | Class III obesity (>40 kg/m2) | 54 (3.4) | 54 (8.17) | 6.26 (3.82–10.28) | <0.01 | | Overweight or obese Classes I-II combined | 967 (60.82) | 486 (73.52) | 2.89 (2.28, 3.65) | <0.01 | | | Overweight or obese Classes I–III combined | 1021 (64.32) | 540 (81.69) | 3.04 (2.41, 3.84) | <0.01 | |
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Adjusted for age, race, sex, alcohol use, smoking, NSAID use, acid suppression therapy, presence of peptic ulcers, Helicobacter pylori (H. pylori) positivity on histopathological examination, and presence of hiatal hernia.
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