|
| Study | Design | Number of cases | Tests | Definition/description for positive findings | Diagnostic yield | Sensitivity/specificity |
|
| Voderholzer et al. (2005) [20] | Prospective | 41 established CD | VCE | Small lesions (aphthoid ulcerations, villous denudation, and patchy erythema) and large lesions (such as cobblestone pattern, deep/fissural ulcerations) | 61% | NA |
| CTEC | Contrast enhancement of the mucosa and the other bowel wall layers, increased density of the peri-intestinal fat representing inflammatory changes and increased vascularity, separation of bowel loops, and possible lymphadenopathy
The length and location of stenotic areas, the presence of fistulae, ulcerations, pseudodiverticulae, and polypous changes of the mucosa | 29% | NA |
|
| Eliakim et al. (2004) [12] | Prospective | 35 suspected CD | VCE | Ulcers/erosions, erythema, aphthae, and nodular lymphoid hyperplasia | 77% | NA |
| CTE | Wall thickening, nodularity in terminal ileum, and ulcers | 20% | NA |
|
| Hara et al. (2006) [21] | Prospective | 17 (8 suspected and 9 established CD) | VCE | Erosions, ulcers, or strictures | 71% | NA |
| CTE | Increased mucosal or wall enhancement, bowel wall thickening > 3 mm, fistulas, or abscesses | 53% | NA |
|
| Solem et al. (2008) [23] | Prospective | 27 | VCE | NA(1) | NA | 83%/53% |
| CTE | NA(1) | NA | 82%/89% |
|
| Jensen et al. (2011) [22] | Prospective | 80 | VCE(2) | More than 3 ulcerations (aphthous lesions or ulcers), irregular ulcers/fissures, or stenosis caused by fibrosis or inflammation | 30%(3) | 100%/91% |
| CTE(2) | Mucosal ulcerations, bowel wall thickening, bowel wall hyperenhancement, small bowel stenosis, creeping fat, dilated vasa recta, and the presence of an abscess or fistula in conjunction to a diseased small bowel segment | 33%(3) | 76%/85% |
|
