Review Article

Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management

Table 4

Comparison of video capsule endoscopy with ileocolonoscopy or push enteroscopy: diagnostic yield or performance for suspected or established Crohn’s disease.

StudyDesignNumber of casesTestsDefinition/description for positive findingsDiagnostic yield

Bloom et al. (2003) [29]Prospective16VCENA56%
ILNA50%

Bourreille et al. (2006) [25]Prospective31 (for postoperative evaluation)VCEErythema, villous denudation, erosion, and ulceration (Rutgeerts score ≥1 for the recurrence at the neoterminal ileum)42–55% for neoterminal ileum, 66–72% for entire small bowel
ILRutgeerts score ≥161%

Hara et al. (2006) [21]Prospective17 (8 suspected and 9 established CD)VCEErosions, ulcers, or strictures71%
ILErosions, ulcers, or strictures65%

Biancone et al. (2007) [26]Prospective17 (for postoperative evaluation)VCESeparate detection of ulcers, strictures, or stenosis in the neoterminal ileum and/or anastomosis94%
ILRutgeerts score ≥194%

Beltrán et al. (2007) [27]Prospective24 (for postoperative evaluation)VCEAphthoid ulcerations, small ulcer, cobblestone pattern, and deep/fissural ulcerations62% (15/21)
ILAphthoid ulcerations, small ulcer, cobblestone pattern, and deep/fissural ulcerations25% (6/21)

Chong et al. (2005) [15]Prospective22 established CDVCEErosions/ulcers77%
PENA14%

Chong et al. (2005) [15]Prospective21 suspected CDVCEErosions/ulcers19%
PENA0

CD, Crohn’s disease; VCE, video capsule endoscopy; IL, ileocolonoscopy; PE, push enteroscopy.