Clinical Study

Lower Viral Response to Pegylated Interferon Alpha 2a Treatment of Chronic Hepatitis B in Roma People in Eastern Slovakia

Table 1

Baseline demographic and virological parameters of the study cohort.

RomaNon-Roma

Count4346
Age (years ± SD)33 ± 8.335 ± 7.50.081
Women11 (25.6%)13 (28.3%)0.680
HBeAg posit9 (20.9%)4 (8.7%)0.093
HBV DNA IU/mL (median(IQR))40900 (28900–588000)27550 (3300–223367)0.025
HBV DNA < 2000 IU/mL3 (9.3%)7 (15.2%)0.219
ALT > 2 ULN22 (51.2%)21 (45.7%)0.603
Staging (Metavir)1.64 ± 1.071.34 ± 1.040.382
Grading (Metavir)1.91 ± 0.872.0 ± 0.760.795
Cirrhosis3 (7.0%)5 (10.9%)0.521

ALT: alanine aminotransferase.