Differential Impacts of Soybean and Fish Oils on Hepatocyte Lipid Droplet Accumulation and Endoplasmic Reticulum Stress in Primary Rabbit Hepatocytes

Figure 4

Soybean oils but not fish oils upregulate GRP94 mRNA and protein levels. Primary hepatocytes were treated with 0.4% or 1% soybean or fish oil-based lipid emulsions. The GPR94 mRNA expression (a) was detected using qRT-PCR and GRP94 protein expression (b, c) was detected by immunohistochemistry at the indicated time points; versus CON. GRP, glucose-regulated protein.