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Gastroenterology Research and Practice
Volume 2016, Article ID 9801063, 11 pages
Review Article

Pretreatment Lymphocyte Monocyte Ratio Predicts Long-Term Outcomes in Patients with Digestive System Tumor: A Meta-Analysis

1Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
2Huiqiao Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
3Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

Received 29 February 2016; Revised 13 June 2016; Accepted 5 July 2016

Academic Editor: Roberto César P. Lima-Júnior

Copyright © 2016 Jingwen Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Example of search criteria in “PubMed”: The following keywords were used in various forms and combinations for “Title/Abstract” based search: “cancer”, “tumor”, “carcinoma”, “neoplasm”, “adenocarcinoma”, “malignant”, “oncology”, “lymphocyte monocyte ratio”, and “monocyte lymphocyte ratio”. Additionally, “neoplasm” was also used in “Medical Subject Headings” based search.

Table S1:This scale is an eight-item instrument that allows for assessment of patient population and selection, study comparability, follow-up, and outcome of interest. Interpretation of the scale is performed by awarding stars, for high-quality elements. Stars are then added up and use to compare study quality in a quantitative manner. A study can be awarded a maximum of one star for each numbered item within the Selection and Outcome categories. A maximum of two stars can be given for Comparability. Quoted phrases are provided in the scale to allow for adjustment to particular studies. 

Table S2:The scale includes eight items in total with four items in selection category, one item in comparability category, and three items in outcome category. Stars were given to high-quality elements. Having seven or more stars is considered good quality.

Table S3: Summary table of studies included in meta-analysis. All studies were conducted between 2013-2016. Country described where the study conducted. Tumor site included colorectal, stomach, esophageal, and liver and pancreas. Treatment described whether the patients received surgical or not. Tumor stage was most often described according to distant metastasis status. For this table, studies were grouped as non-metastatic stage (NMS), metastatic stage (MS) or mixed stage. Clinical outcomes include overall survival (OS), cancer-specific survival (CSS), relapse-free survival (RFS), and disease-free survival (DFS). 

  1. Supplementary Material