Comparison of Inflammation-Based Prognostic Scores in a Cohort of Patients with Resectable Esophageal Cancer

Table 4

Multiple Cox regression models for overall survival for various proposed ways to account for CRP and albumin effect. Results for multiple Cox regression model refer to adjustment for the variables reported in Table 3. Hazard ratios (HR) with 95% confidence intervals (CI) and values (p) and proportions of explained variation (PEV). Full model PEV = 21.8%.

Variables	Multiple; HR (95%, CI)	value	PEV
Alb < 35	0.92 (0.54–1.58)	0.763	0.0
CRP > 1	1.47 (0.97–2.24)	0.070	0.3
GPS		0.287	0.3
1 versus 0	1.37 (0.93–2.04)	0.116
2 versus 0	1.17 (0.52–2.60)	0.708
mGPS		0.159	0.3
1 versus 0	1.55 (0.99–2.43)	0.056
2 versus 0	1.17 (0.53–2.60)	0.705
log(CRP/Alb)	1.02 (0.95–1.09)	0.684	0.0
CRP/Alb > 0.95	0.89 (0.44–1.84)	0.759	0.0

HR for log2-transformed variables quantify the effect of a doubling of the respective variable.