Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma

Figure 2

Recurrent mutations verified by Sanger sequencing. Frequent mutations in 2 cases were verified by Sanger sequencing. Each mutation was heterozygous and led to a change in the amino acid sequence of the encoded protein. None of the mutations reside in the DNA of peripheral lymphocytes. The black arrows indicate the mutation site. N: peripheral lymphocytes. T: HCC sample.