Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma

Table 1

Clinicopathologic characteristics of 5 hepatocellular carcinoma patients used for exome sequencing.

Patient ID

Gender

Age

Aetiology

Liver cirrhosis

Edmondson grade

Adjacent invasion

Vascular invasion

Lymph node

Metastasis

Tumour size (cm)

TNM stage

BCLC; stage

Patient 1

Male

45

HBV

Yes

II

No

No

No

No

2.8 × 2.8

II

A

Patient 2

Male

52

HBV

Yes

II

No

No

No

No

2 × 1.8

I

A

Patient 3

Male

42

HBV

No

II

No

No

No

No

2 × 1.8

I

A

Patient 4

Male

52

HBV

No

I

No

No

No

No

2 × 1.8

I

A

Patient 5

Male

61

HBV

Yes

II

No

No

No

No

2.2 × 2.2

II

A

Tumour staging was based on the 7th edition of tumour-node-metastasis classification of the American Joint Committee on Cancer Staging Manual. HBV: hepatitis B virus; BCLC: Barcelona clinic liver cancer.