Research Article

Utility of Endoscopic Examination in the Diagnosis of Acute Graft-versus-Host Disease in the Lower Gastrointestinal Tract

Table 2

Patient characteristics.

Number186
Average age, year (range)50.6 (19–82)
Gender
 Male122
 Female64
Average inspection days after transplantation
CS41.3 (13–100)
Average number of biopsy specimens4.9
Primary disease
 Acute leukemia120
 Malignant lymphoma38
 Myelodysplastic syndrome16
 Chronic myelogenous leukemia5
 Others7
Stem cell source
 Cord blood stem cell transplantation125
 Bone marrow transplantation36
 Alloperipheral blood stem cell transplantation25
Previous treatment
 FLU-based regimen161
 CY/TBI or CY/BU25
Preservation of GVHD
 FK + MMF72
 MTX + CyA/FK/MMF57
 CyA or FK57
Extent of endoscopic insertion
 Up to the left-side colon15
 Until the right-side colon17
 Terminal ileum154

FLU: fludarabine; CY: cyclophosphamide; TBI: total body irradiation; BU: busulfan; CyA: cyclosporin A; MTX: methotrexate; MMF: mycophenolate mofetil.