Utility of Endoscopic Examination in the Diagnosis of Acute Graft-versus-Host Disease in the Lower Gastrointestinal Tract

Table 4

Summary of outcomes of lower GI.

	Accuracy (%)	Sensitivity (%)	Specificity (%)	PPV (%)	PPV (%); (Grade III or IV)
Terminal ileum
Edema	36.3	40.0	81.8	96.2	65.4
Redness	40.0	44.0	81.8	96.5	66.7
Erosion	28.9	31.2	90.9	97.5	70.0
Ulcer	5.2	5.6	100	100	71.4
Villous atrophy	49.6	54.4	100	100	67.6
Atrophy of the ileocecal valve	69.2	71.3	55.6	87.7	50.6
Mucosal exfoliation	12.3	14.4	100	100	88.9
No remarkable findings	22.2	24.0	27.3	78.9	7.9
Colon
Edema	73.0	75.4	53.3	94.9	50.7
Redness	52.2	53.2	60.0	93.8	59.8
Erosion	38.2	40.9	93.3	98.6	74.6
Ulcer	8.6	9.4	100	100	81.3
Low vascular permeability	80.0	81.3	33.3	93.3	50.3
Tortoise shell-like mucosae	67.6	49.7	53.3	94.4	48.4
Mucosal exfoliation	8.1	8.8	100	100	93.3
No remarkable findings	6.5	7.1	80.0	75.0	0.0

PPV: positive predictive value.