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Gastroenterology Research and Practice
Volume 2017, Article ID 2386291, 6 pages
Research Article

Efficacy, Safety, and Overall Quality of Life of Endoscopic Submucosal Dissection for Early Colorectal Cancer in Elderly Patients

Department of Gastroenterology, Ji’nan Central Hospital Affiliated to Shandong University, Ji’nan 250012, China

Correspondence should be addressed to Jingyu Zhu; moc.361@yjzbjs

Received 21 April 2017; Revised 1 June 2017; Accepted 5 June 2017; Published 3 July 2017

Academic Editor: Haruhiko Sugimura

Copyright © 2017 Liang Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. Studies reporting the treatment of early colorectal cancer (ECC) by endoscopic submucosal dissection (ESD) in elderly patients are lacking in China. The aim was to evaluate the efficacy, safety and overall quality of life of elderly patients with ECC who undergoing ESD. Methods. Three hundred and seventy-nine patients with 401 colorectal lesions entered into our study from March 2013 to March 2016 (Patients with an age 70 years old or older were divided into the elderly group and those who were less than 70-year-old entered the non-elderly group). Results. No significant differences were found in sex ratio, body mass index, location, endoscopic classification, pathological pattern, lesion size, mean procedure time, hospitalization days, complete excision, and en bloc resection rate between the two groups (). No significant differences were observed between the groups in terms of complications during and after ESD procedure (). There were no statistical differences between two groups in Quality of life index (QL-Index) and European Organization for Research and Treatment quality of life version 3.0 questionnaire (EORTC QLQ-C30) scores (). Conclusion. ESD was relatively safe and effective for elderly patients with ECC, and it may be an recommended first-line treatment.