Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis

Figure 2

FGF21 deficiency markedly reduces experimental colitis-induced body weight loss and eWAT lipolysis. FGF21-KO mice and C57BL/6J mice were treated with 2.5% dextran sodium sulfate (DSS) for 7 days as described in the Materials and Methods. (a) Body weight change. (b) Linear correlation of the body weight change and serum FGF21 levels. (c) eWAT/body weight ratio. (d) Adipocyte size image. (e) Serum glycerol. (f) Serum FFA.

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