Gastroenterology Research and Practice / 2017 / Article / Tab 1

Clinical Study

Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity

Table 1

Demographic data and high-resolution manometry and impedance results.

ItemsFHRHIndependent samples t-test, chi-square test, or Fisher’s exact testHVANOVA, chi-square test, or Fisher’s exact test

Age (mean ± SD, years)57.5 ± 47.051.0 ± 12.854.8 ± 12.3
Male/female (n)56/9143/4816/20
Dysphagia (n, %)5 (3.4)1 (1.0)0 (0)
Belching (n, %)12 (8.1)25 (27.4)2 (5.5)
Globus (n, %)13 (8.8)4 (4.3)1 (2.7)
Chest pain (n, %)24 (16.3)10 (10.9)0 (0)
Upper abdominal pain (n, %)8 (5.4)4 (4.3)3 (8.3)
Abdominal distension (n, %)5 (3.4)1 (1.0)2 (5.5)
LESP (mean ± SD, mmHg)17.3 ± 10.317.1 ± 10.522.1 ± 9.4
LESL (mean ± SD, cm)3.8 ± 0.93.7 ± 0.73.9 ± 0.9
LESRP (mean ± SD, mmHg)5.2 ± 4.64.5 ± 4.25.7 ± 4.3
IRP (mean ± SD, mmHg)8.1 ± 4.77.9 ± 5.27.3 ± 4.5
UESP (mean ± SD, mmHg)82.8 ± 31.581.7 ± 35.988.8 ± 36.3
DEA (mean ± SD, mmHg)68.3 ± 30.561.9 ± 26.278.3 ± 36.4
DCI (mean ± SD, mmHg·s·cm)806.3 ± 752.5575.7 ± 495.11060.0 ± 635.5
Ineffective esophageal motility (n (%))40 (27.2)38 (41.7)0 (0)
Fragmented peristalsis (n (%))5 (3.4)9 (9.9)0 (0)
Total bolus transit time, s6.5 ± 1.46.5 ± 1.36.2 ± 1.1
Complete bolus transit rate, %75.4 ± 30.972.7 ± 32.194.7 ± 11.5
Hiatus hernia (n (%))4 (2.7)8 (8.8)1 (2.8)

HV: healthy volunteers; FH: functional heartburn; RH: reflux hypersensitivity; LESP: lower esophageal sphincter pressure; LESL: lower esophageal sphincter length; LESRP: lower esophageal sphincter residual pressure; IRP: integrated relaxation pressure; UESP: upper esophageal sphincter pressure; DEA: distal esophageal amplitude; DCI: distal contractile integral.

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