Clinical Study

Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity

Table 2

Results of 24-hour multichannel intraluminal impedance and pH recording.

ItemsFHRHIndependent sample t-test, chi-square test, or Fisher’s exact testHVANOVA, chi-square test, or Fisher’s exact test

DeMeester2.7 ± 2.43.3 ± 2.43.0 ± 2.4
Acid exposure upright (%)1.0 ± 1.41.4 ± 1.41.4 ± 1.7
Acid exposure recumbent (%)0.1 ± 0.20.1 ± 0.20.1 ± 0.2
Acid exposure total (%)0.6 ± 0.70.8 ± 0.80.7 ± 0.9
Bolus exposure upright (%)1.8 ± 1.52.6 ± 2.01.9 ± 1.4
Bolus exposure recumbent (%)0.3 ± 0.70.4 ± 0.70.2 ± 0.4
Bolus exposure total (%)0.9 ± 0.81.5 ± 1.11.0 ± 0.7
Proximal acid event (n)5.6 ± 5.69.8 ± 8.95.4 ± 4.4
Proximal nonacid event (n)6.9 ± 5.611.6 ± 10.86.8 ± 5.7
Proximal total reflux event (n)12.3 ± 9.020.9 ± 16.812.2 ± 7.5
Distal acid reflux event (n)8.4 ± 8.013.5 ± 11.28.6 ± 7.5
Distal nonacid reflux event (n)16.6 ± 11.125.0 ± 15.316.8 ± 9.8
Distal total reflux event (n)25.0 ± 14.438.5 ± 20.925.1 ± 14.4
PSPW index (%)47.0 ± 17.933.8 ± 15.873.6 ± 11.7
MNBI (ohms)2972.0 ± 775.62485.3 ± 939.23290.1 ± 613.5

HV: healthy volunteers; FH: functional heartburn; RH: reflux hypersensitivity; PSPW index: postreflux swallow-induced peristaltic wave index; MNBI: mean nocturnal baseline impedance.