Gastroenterology Research and Practice

Research Article

Serum Alanine Aminotransferase Levels within Normal Range Have Different Associations with Augmentation Index and Other Cardiometabolic Risk Factors in Nondrinkers and Drinkers: A Chinese Community-Based Analysis

Table 1

Characteristics of nondrinkers according to the quartiles of serum ALT levels.


Characteristics	Quartile 1 ≤10 U/L ()	Quartile 2 11–20 U/L ()	Quartile 3 21–30 U/L ()	Quartile 4 31–40 U/L ()	value

Age (year)	44 (33–59)	54 (43–67)	54 (45–63)	52 (44–59)	<0.001
Men (%)	51 (14.7)	436 (26.3)	279 (38.4)	115 (43.9)	<0.001
BMI (kg/m²)	22.97 (20.70–25.76)	24.98 (22.76–27.70)	26.49 (24.04–28.91)	26.95 (24.98–29.68)	<0.001
Hypertension (%)	77 (22.2)	649 (39.2)	362 (49.8)	127 (48.5)	<0.001
DM (%)	18 (5.2)	176 (10.6)	94 (12.9)	41 (15.6)	<0.001
SBP (mmHg)	116 (106–129)	124 (113–139)	129 (119–142)	127 (118–142)	<0.001
DBP (mmHg)	72 (68–80)	77 (70–81)	80 (71–86)	80 (72–87)	<0.001
HR (beats/minute)	76 (70–83)	75 (69–82)	75 (68–82)	75 (69–83)	0.095
Triglyceride (mmol/L)	0.97 (0.75–1.33)	1.27 (0.90–1.74)	1.52 (1.06–2.19)	1.62 (1.16–2.41)	<0.001
HDL-c (mmol/L)	1.54 (1.30–1.79)	1.43 (1.22–1.69)	1.34 (1.15–1.58)	1.31 (1.13–1.52)	<0.001
LDL-c (mmol/L)	2.41 (1.95–2.95)	2.75 (2.28–3.27)	2.91 (2.46–3.38)	3.03 (2.57–3.43)	<0.001
FBG (mmol/L)	4.86 (4.57–5.16)	4.95 (4.60–5.38)	5.05 (4.67–5.45)	5.15 (4.78–5.60)	<0.001
AIx (%)	79 (70–88)	82 (74–89)	82 (74–89)	82 (72–91)	0.015

ALT: alanine aminotransferase; BMI: body mass index; DM: diabetes mellitus; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; FBG: fasting blood glucose; AIx: augmentation index.