Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection
Table 4
Comparison of clinical factors in circulatory adverse event due to sedation during endoscopic submucosal dissection in the MP group.
Nonadverse event ()
Adverse event ()
value
Odds ratio (95% CI)
Univariate
Gender, n (%)
0.179
—
Male/female
50 (63.3)/29 (36.7)
23 (48.9)/24 (51.1)
Age ≥ 75 (yr)
15 (19.0)
13 (27.7)
0.26
—
Body mass index (kg/m2)
24.9 ± 3.2
24.9 ± 2.7
0.916
—
Smoking history, n (%)
0.014
0.15 (0.03–0.68)
Non- or ex-smoker
61 (77.2)
45 (95.7)
Current smoker
18 (22.8)
2 (4.3)
Alcohol abuse, n (%)
10 (12.7)
5 (10.6)
0.735
—
Regular use of sedatives or psychotrophic drugs, n (%)
3 (3.8)
1 (2.1)
0.61
—
Midazolam (mg)
5.6 ± 1.7
5.5 ± 1.5
0.735
—
Propofol (mg)
91.3 ± 64.7
91.9 ± 85.6
0.961
—
Procedure time (min)
43.9 ± 29.5
46.0 ± 36.3
0.716
ASA physical status, n (%)
0.631
—
1/2
61 (77.2)
38 (80.9)
3
18 (22.8)
9 (19.1)
Values are mean ± SD or n (%) of patients. SD: standard deviation; MP: sedation with midazolam plus intermittent propofol injection; ASA: American Society of Anesthesiologists.
