Genetic Polymorphisms: A Novel Perspective on Acute Pancreatitis

Figure 1

The relationship between different pathophysiological processes implicated in AP and susceptibility genes is concluded as follows: PRSS1: cationic trypsinogen; SPINK1: serine protease inhibitor Kazal type 1; CTRC: chymotrypsin C; ACE: angiotensin-converting enzyme; MIF: migration inhibitory factor; iNOS: inducible nitric oxide synthase; COX-2: cyclooxygenases 2; MYO9B: myosin IXB; TLRs: toll-like receptors; MCP-1: monocyte chemoattractant protein-1; HBDs: human β-defensin 2; MBL2: mannose-binding lectin 2; TNF-α: tumor necrosis factor-α; IL-10: interleukin 10; TLR4: toll-like receptor 4.